The main goal of this work was to print living cells with an open-source printer, part of the new logic of personalized regenerative medicine.
The presented study provides skin equivalent 3D printing proof of concept with strong indicators such as viable cells integration and generation of a 3D network of neo-secretion ECM (Extra-Cellular Matrix), making the printed skin equivalents as close as possible to the real human skin.
It was thus proved that printed cells survived and growth following the printing process thanks to the developed bio-ink.
Skin equivalents were successfully printed and behave similarly to human skin.
These results are really encouraging with high potential applications in the field of regenerative medicine and 3D organ model systems.
About Léa Pourchet
Léa Pourchet works at Lyon University in an academic Institute specialized in chemistry and biochemistry (ICBMS), France. She obtained a double degree as polymer engineer and research master “Matériaux innovants” of one of the top French Engineer school (Ecole centrale). She is currently research engineer in charge of 3D bioprinting development and PhD student in the group of Dr.Christophe Marquette. Her areas of expertise focus in the bioprinting especially the interaction between biomaterials and cells.
She is also a manager of the new 3D platform 3D FAB specialized in bioprinting for biomedical and diagnostic fields.
About 3d.FAB, Université de Lyon 1
The 3d.FAB platform is host by the Université Lyon1 and is dedicated to 3D printing and additive technologies for life science.
3d.FAB is part of the Biochip group of the UMR5246 (ICBMS).
In the field of biochemistry, especially diagnosis with prototyping 3D lab-on-chip, novel materials for 3D medical devices, biocompatible polymers and cell-size 3D printing.
In the field of regenerative medicine through dedicated living cells and tissues printers.